Hydrogen Water Boosts Cancer-Fighting Effects of Vitamin C and Platinum

Carcinostatic effects of alkanoyl ascorbate plus platinum nano-colloid and stabilization of the esterolytically resultant ascorbate by hydrogen

Research hubs: Digestive System

Evidence type
Laboratory study (cells or tissue)
Authors
Shinya Kato, Yasukazu Saitoh, Nobuhiko Miwa
Journal
Human Cell
Year
2021
DOI
10.1007/s13577-020-00462-3
Study Type
Cell Culture
Outcome
Positive
Peer Reviewed
Yes
Country
Japan
Health Condition
Esophageal Cancer
Body System
Digestive System

This research was done on cells or tissue in a lab, not in people or animals.

TL;DR

A combination of a modified vitamin C compound and tiny platinum particles in hydrogen-rich water was found to be more effective at stopping the growth of esophageal cancer cells than either treatment alone.

Key Finding

A combination of modified vitamin C and platinum nanoparticles reduced esophageal cancer cell viability more effectively than either component alone, with enhanced effects when paired with hydrogen-rich water.

Summary

Researchers tested whether a modified form of vitamin C (called 6-O-palmitoyl ascorbate) combined with tiny platinum particles could slow the growth of esophageal cancer cells in laboratory dishes. They found that this combination was more effective at stopping cancer cell growth than either ingredient alone, and that hydrogen-rich water (water containing dissolved hydrogen gas) helped preserve the vitamin C and made it work better.

Practical Takeaway

This is early laboratory research in cancer cells, not human studies, so it cannot yet be applied to actual cancer treatment. While the results are interesting, hydrogen-rich water's role appears to be stabilizing the vitamin C compound rather than providing direct anti-cancer effects. Much more research, including human trials, would be needed before any therapeutic claims could be made.

Abstract (excerpt)

Carcinostatic effects of combined use of ascorbic acid (Asc), 2-O-phospho- or 6-O-palmitoyl ascorbate (Asc2Phos, Asc6Palm) or diverse alkanoyl Asc, and nano-sized platinum-poly(N-vinyl-pyrrolidone) colloid (PVP-Pt; 2-nm diameter) were examined on human esophagus carcinoma-derived cells KYSE70. Cell…

Read the full abstract via DOI