Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report

Duanming Du, Feng Mu, Ji-Bing Chen, Ke-Cheng Xu, Tianyu Lu

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DOI: 10.2147/OTT.S235195 DOI is the universal ID for this study.

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Lung cancer is the most common type of tumor, prone to contralateral lung, bone and brain metastasis. We report a 44-year-old woman diagnosed with lung cancer with multiple metastases in November 2015. Oral targeted drugs were initiated after the removal of brain metastases, and most lesions remained stable for 28 months. In March 2018, intracranial multiple metastases, as well as hydrocephalus accumulation in the third ventricle and lateral ventricles, and metastases in bone, adrenal gland, liver were noted. Hydrogen-gas monotherapy was started to control the tumor a month later. After 4 months, the size of multiple brain tumors was reduced significantly, and the amount of hydrocephalus in the third ventricle and lateral ventricles reduced significantly. After 1 year, all brain tumors had disappeared, and there were no significant changes in metastases in the liver and lung. These data show that, after standard treatments had failed, hydrogen-gas monotherapy elicited significant effective control of tumors (especially those in the brain), and survival time was lengthened. Keywords: hydrogen gas, lung cancer, brain metastasis, extrapulmonary metastasis

Publish Year 2019
Country China
Rank Positive
Journal OncoTargets and Therapy
Primary Topic Brain
Secondary TopicCancer
Model Human
Tertiary TopicOncogenesis
Vehicle Gas
pH N/A
Application Inhalation