Antioxidant Effect of Hydrogen Nanobubble Contributes to Suppression of Tumor Cell Growth

Atsushi Taninaka, Gjergj Dodbiba, Hidemi Shigekawa, Hirofumi Matsui, Hiromi Kurokawa, Hiromu Ito, Toyohisa Fujita, Yuezhou Wei

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DOI: 10.26717/BJSTR.2019.19.003361 DOI is the universal ID for this study.

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The antitumor effect of hydrogen nanobubble was evaluated in vitro and in vivo. Cancer cell growth was inhibited in the hydrogen nanobubble-containing medium compared to the non-containing medium (in vitro). Tumor growth was significantly suppressed in the middle stage of transplantation (in vivo). We reported that hydrogen nanobubbles is a ROS scavenger, therefore apoptosis due to ROS reduction may be induced in these results.

Publish Year 2019
Country Japan
Rank Positive
Journal Biomedical Journal of Scientific and Technical Research
Primary Topic Whole Body
Secondary TopicCancer
Model Cell Culture
Tertiary TopicOncogenesis
Vehicle Gas (Sustained Release)
pH N/A
Application Culture Media