NIR-Activatable Heterostructured Nanoadjuvant Cop/Nicop Executing Lactate Metabolism Interventions ...
2023 - Whole Body - Immune Regulation
Near-infrared (NIR) laser-induced photoimmunotherapy has aroused great interest due to its intrinsic non-invasiveness and spatiotemporal precision, while immune evasion evoked by lactic acid (LA) accumulation severely limits its clinical outcomes. ...
Micromotor-Enabled Active Hydrogen and Tobramycin Delivery for Synergistic Sepsis Therapy
2023 - Whole Body - Sepsis
Sepsis is a highly heterogeneous syndrome normally characterized by bacterial infection and dysregulated systemic inflammatory response that leads to multiple organ failure and death. Single anti-inflammation or anti-infection treatment exhibits ...
Evaluation of the safety and potential lipid-lowering effects of oral hydrogen-rich coral calcium ...
2023 - Whole Body - Metabolic Syndrome
Background: Metabolic syndrome is characterized by a cluster-like occurrence of conditions such as hypertension, hyperglycaemia, elevated low-density lipoprotein (LDL) cholesterol or triglycerides (TG) and high visceral fat. Metabolic syndrome is ...
Hydrogen prevents lipopolysaccharide-induced pulmonary microvascular endothelial cell injury by ...
Background: Sepsis is a type of life-threatening organ dysfunction that is caused by a dysregulated host response to infection. The lung is the most vulnerable target organ under septic conditions. Pulmonary microvascular endothelial cells (PMVECs) ...
Micromotor-Enabled Active Hydrogen and Tobramycin Delivery for Synergistic Sepsis Therapy
2023 - Whole Body - Sepsis
Sepsis is a highly heterogeneous syndrome normally characterized by bacterial infection and dysregulated systemic inflammatory response that leads to multiple organ failure and death. Single anti-inflammation or anti-infection treatment exhibits ...
Hydrogen-rich saline regulates NLRP3 inflammasome activation in sepsis-associated encephalopathy rat ...
Sepsis-associated encephalopathy (SAE) is characterised by long-term cognitive impairment and psychiatric illness in sepsis survivors, associated with increased morbidity and mortality. There is a lack of effective therapeutics for SAE. Molecular ...