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ECG changes during the experimental human dive HYDRA 10 (71 atm/7,200 kPa)
Electrocardiogram (ECG) analysis was performed in three human divers during a 71 atm (7,200 kPa) saturation dive (COMEX HYDRA 10 experiment). The inhaled gas mixture was slightly hyperoxic; its composition was basically helium and oxygen. Hydrogen was introduced during compression and its partial…
Effect of alkaline ionized water on reproduction in gestational and lactational rats
Alkaline ionized water (AKW) produced by electrolysis was given to gestational and lactational rats, and its effect on dams, growth of fetuses and offsprings were investigated. The results showed that the intake of food and water in dams increased significantly when AKW was given from the latter…
Psychophysiological reactions in humans during an open sea dive to 500 m with a hydrogen-helium-oxygen mixture
Six commercial divers were investigated for neurological and psychosensorimotor responses during an open sea dive to 500 m with a hydrogen-helium-oxygen mixture containing 49% hydrogen. Results showed only moderate neurological symptoms of high-pressure nervous syndrome, whereas the narcotic effect…
Production, metabolism, and excretion of hydrogen in the large intestine
Hydrogen is produced during fermentation in the large intestine and may be excreted in breath and flatus or further metabolized by the flora. However, there is little information about total H2 excretion from different substrates or the extent to which it is metabolized in the colon. We have…
Maintaining intestinal H2 balance: credit the colonic bacteria
Dietary fibre and health: the role of hydrogen production
The biological basis for the epidemiological association between high dietary fibre intakes and reduced disease incidence in Man is not fully understood. It is proposed that molecular hydrogen, produced in quite large amounts as a by-product of colonic fermentation of dietary fibre and unabsorbed…
Effects of a H2-He-O2 mixture on the HPNS up to 450 msw
A H2-He-O2 mixture with 54 to 56% hydrogen was studied with 6 subjects (professional divers) during 2 dives to 450 m. The 38-h compression was the same as that used with other types of breathing mixtures (He-O2 and He-N2-O2). The results obtained during compression and during the stay at 450 m…
Hydra V Hydrogen Experimental Dive To 450 Meters
ABSTRACT HYDRAV was performed in COMEX Marseille hyperbaric Research Center in May and June 1985.During this Experiment, 6 divers lived at a simulated depth of 450 meters in a hyperbaric atmosphere composed of hydrogen, helium and oxygen (hydreliox). Tradition deep diving with helium is limited…
Hydrogen ion dynamics and cancer: An appraisal
AbstractThe concentration of hydrogen ions plays a critical role in all biochemical processes, including multiple enzymatic reactions, and in the regulation of metabolism. The acid‐base aspects of metabolism as applied to cancer are considered. Preliminary data are presented. The primary concept…
Solubility of inert gases in dog blood and skeletal muscle
Solubility of H2, Ar, CH4 and SF6 was determined at 310 K (37 degrees C) in water, in saline (0.154 mol NaCl/l H2O), in plasma and whole blood of dogs, and in homogenates of the dog gastrocnemius muscle. The liquids were equilibrated with pure gases, and the dissolved gases were extracted…
Response of five established solid transplantable mouse tumors and one mouse leukemia to hyperbaric hydrogen
A variety of transplantable mouse tumors were used in experiments to determine the efficacy of hyperbaric hydrogen treatment. After 7 continuous days of hyperbaric hydrogen treatment, no inhibition of tumor growth was observed.
Hyperbaric hydrogen therapy: A possible treatment for cancer
Hairless albino mice with squamous cell carcinoma were exposed to a mixture of 2.5 percent oxygen and 97.5 percent hydrogen at a total pressure of 8 atmospheres for periods up to 2 weeks in order to see if a free radical decay catalyzer, such as hydrogen, would cause a regression of the skin…
Diffusivity of various inert gases in rat skeletal muscle
Krogh's diffusion constant (K) was determined for various inert gases in isolated rat abdominal muscle at 37 degrees C by measuring the amount of gas diffusing per unit time and partial pressure difference through a portion of the muscle of known surface area and thickness. The following mean…
Solubility of various inert gases in rat skeletal muscle
For the determination of solubility coefficients, isolated rat abdominal muscles were equilibrated at 37 degrees C with various inert gases saturated with water vapor. After rapid transfer into a closed chamber containing room air the amount of gas extracted from the sample by diffusion was…
Production and Excretion of Hydrogen Gas in Man
Technics employing intestinal infusions of gas were used to study H2 production in the human intestine. The volume of H2 in the bowel of 10 normal subjects varied from 0.06 to 29 ml. H2 production, which averaged 0.24 ml per minute in the fasting state, sharply increased after intestinal…