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Regulation of functions of animal cells by reduced water and its medical application
Electrolyzed Strong Acid Aqueous Solution Irrigation Promotes Wound Healing in a Burn Wound Model
Abstract: The purpose of the study was to understand the effectiveness of electrolyzed strong acid aqueous solution (ESAAS) for acceleration of epithelialization in a rat burn wound model. Eighteen anesthetized Sprague‐Dawley rats received 30% total body surface area third‐degree burns, and 2 days…
Treatment for Abdominal Aortic Graft Infection: Irrigation with Electrolyzed Strong Aqueous Acid, In-situ Grafting, and Omentoplasty
We report on successful surgical treatment of consecutive three patients with infection of an abdominal aortic graft, Therapy involved a combination of removal of the infected graft, elaborate debridement, irrigation with electrolyzed strongly acidic aqueous solution (ESAAS), in-situ regrafting…
Fundamental Properties of Electrolyzed Water
Electrolyzed Water (Acidic Electrolyzed Water, Alkaline Electrolyzed Water) has recently attracted the interest of researchers in various fields such as medicine, agriculture and food processing. in this study, we investigated the preservability of Electrolyzed Water produced in a two-cell…
Bactericidal effect of electrolyzed neutral water on bacteria isolated from infected root canals
The purposes of this study were to examine the time-related changes in pH, oxidation-reduction potential, and concentration of chlorine of electrolyzed neutral water and to evaluate the bactericidal effect of electrolyzed neutral water against bacteria from infected root canals. Various properties…
Effectiveness of Acidic Oxidative Potential Water in Preventing Bacterial Infection in Islet Transplantation
At a number of points in the current procedures of islet isolation and islet culture after the harvesting of donor pancreata, microorganisms could potentially infect the islet preparation. Furthermore, the use of islets from multiple donors can compound the risks of contamination of individual…
Electrolyzed and Natural Reduced Water Exhibit Insulin-Like Activity on Glucose Uptake into Muscle Cells and Adipocytes
In the type 2 diabetes, it has become clear that reactive oxygen species (ROS) cause reduction of glucose uptake by inhibiting the insulin-signaling pathway in muscle cells and adipocytes. We demonstrated that electrolyzed-reduced water (ERW) scavenges ROS and protects DNA from oxidative damage1)…
Influences of alkaline ionized waler on milk yield, body weight of offspring and perinatal dam in rats.
The authors previously reported that male offspring of mothers rats given alkaline ionized water (AKW) showed a significantly higher body weight by day 14 after birth than did offspring of mother rats given tap water (TPW); furthermore, marked myocardial necrosis and fibrosis were observed…
Histopathological influence of alkaline ionized water on myocardial muscle of mother rats
We have reported that a marked necrosis and subsequent fibrosis of myocardium occurred among male rats 15 weeks old given alkaline ionized water (AKW) during gestation and suckling periods, and after weaning. In this study, it was examined whether similar lesions would occur in mother rats which…
The Nordenau-Phenomenon—Facts and Hypotheses
The reaction shown by the 515 test-subjects (318 female, 197 male) to the so-called “Nordenau-Phenomenon” (meaning an old slate tunnel with an underground source of spring-water, which are said to have a healing effect) was verified. Chronically ill and incurable people have been pilgrimaging there…
Electrolyzed Reduced Water Which Can Scavenge Active Oxygen Species Supresses Cell Growth and Regulates Gene Expression of Animal Cells
Active oxygen species are considered to cause extensive oxidative damage to biological macromolecules, which bring about a variety of diseases as well as aging. Reduced water produced near cathode during electrolysis of water exhibits high pH, low dissolved oxygen, extremely high dissolvedmolecular…
Effect of electrolyzed water intake on lifespan of autoimmune disease prone mice
Recent studies on electrolyzed water indicate that anode or acidic water is most effective as disinfectants; whereas, reduced or alkaline water processed through cathode is used as safe drinking water. The present drinking water study was undertaken in two strains of autoimmune disease prone mice…
Degradation of Myocardiac Myosin and Creatine Kinase in Rats Given Alkaline Ionized Water
Recently, the authors have shown that marked necrosis and fibrosis of myocardium were observed in rats given alkaline ionized water (AKW). To clarify the cause of myocardial lesions, the activities of myosin ATPase, actomyosin ATPase and creatine kinase (CK) in myocardium of rats given AKW at 15…
Decompression comparison of helium and hydrogen in rats
Lillo, R. S., E. C. Parker, and W. R. Porter.Decompression comparison of helium and hydrogen in rats. J. Appl. Physiol. 82(3): 892–901, 1997.—The hypothesis that there are differences in decompression risk between He and H2 was examined in 1,607 unanesthetized male albino rats subjected to dives…
Successful Treatment of Mediastinitis after Cardiovascular Surgery Using Electrolyzed Strong Acid Aqueous Solution
Dilute povidone-iodine solution has been widely used as an irrigant for the treatment of mediastinitis. However, its use is not without adverse effects and often cause? poor growth of pinulation tissues. To avoid the problems seen with the use of povidone-iodine solution, we applied electrolyzed…
Treatment of Infectious Skin Defects or Ulcers with Electrolyzed Strong Acid Aqueous Solution
Abstract: A chronic ulcer with an infection such as methicil‐lin‐resistant Staphylococcus uureus is hard to heal. Plastic and reconstructive surgeons often encounter such chronic ulcers that are resistant to surgical or various conservative treatments. We applied conservative treatment using…
INFLUENCE OF ALKALINE IONIZED WATER ON RAT ERYTHROCYTE HEXOKINASE ACTIVITY AND MYOCARDIUM
Alkaline ionized water (AKW) produced by the electrolysis of tap water (TPW) was given to pregnant rats throughout gestation. AKW was subsequently given to infants as a test group until 15 weeks old to determine changes in body and organ weights, erythrocyte hexokinase (HK) activity…
Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage
Active oxygen species or free radicals are considered to cause extensive oxidative damage to biological macromolecules, which brings about a variety of diseases as well as aging. The ideal scavenger for active oxygen should be 'active hydrogen'. 'Active hydrogen' can be produced in reduced water…
Trial of Electrolyzed Strong Acid Aqueous Solution Lavage in the Treatment of Peritonitis and Intraperitoneal Abscess
Electrolyzed strong acid aqueous solution is acidic water that contains active oxygen and active chlorine and possesses a redox potential. We performed peritoneal and abscess lavages with an electrolyzed strong acid aqueous solution to treat 7 patients with peritonitis and intraperitoneal…