All Studies
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Electrolyzed Reduced Water Induces Differentiation in K-562 Human Leukemia Cells
Electrolyzed reduced water (ERW) is known to scavenge reactive oxygen species (ROS) which is related to malignant tumor phenotypes. We attempted to clarify the effect of ERW on tumor phenotypes of K562 human leukemia cells. Treatment of K562 cells with ERW resulted in growth arrest, morphological…
Suppression of glutamate-induced neural cell death by electrolyzed-reduced water
Electrolyzed-reduced water (ERW) produced by electrolyzing water in cathode side has the ability to scavenge reactive oxygen species (ROS). Here, we investigated the effect of ERW on oxidative stress-induced neural cell death by glutamate. When cell viability assay was performed using primary rat…
Electrolyzed-Reduced Water as Artificial Hot Spring Water
Water-electrolysis with ion-exchange membranes followed by passing through ac- tivated carbon filter conducted to produce electrolyzed-reduced water that has neutral and reductive characteristics. In addition, the electrolyzed-reduced water was also confirmed characteristic of antioxidative…
The Suppressive Effect of Electrolyzed Reduced Water on Lipid Peroxidation
We examined the suppressive effect on lipid peroxidation of electrolyzed reduced water (ERW), which exhibited reactive oxygen species (ROS)-scavenging activity in vitro and in cultured cells. The oxidation of linoleic acid by 2, 2’-azobis (2-amidinopropane) hydrochloride (AAPH) was suppressed…
Protective mechanism of reduced water against alloxan-induced pancreatic β-cell damage: Scavenging effect against reactive oxygen species
Reactive oxygen species (ROS) cause irreversible damage to biological macromolecules, resulting in many diseases. Reduced water (RW) such as hydrogen-rich electrolyzed reduced water and natural reduced waters like Hita Tenryosui water in Japan and Nordenau water in Germany that are known to improve…
Clinical Applications of Electrolyzed-Reduced Water
A very important and interesting paper was submitted by Happe in January ‘97 (1). He says, the oldest life forms ‘Desulfoviorio gigas’ 3.8 billion years old, had developed an enzyme ‘hydrogenase’, to activate hydrogen,namely to split molecular hydrogen to atomic hydrogen. Here,the question…
Chronic Administration with Electrolyzed Alkaline Water Inhibits Aspirin-induced Gastric Mucosal Injury in Rats through the Inhibition of Tumor Necrosis Facter-.ALPHA. Expression
Neutrophils activation and tumor necrosis factor-α (TNF-α) induction play critical roles in aspirin-induced gastric mucosal injury. The aim of the present study was to determine whether electrolyzed alkaline water (EAW) can ameliorate aspirin-induced gastric mucosal injury in rats, and whether EAW…
Telomere Shortening in Cancer Cells by Electrolyzed-Reduced Water
Electroly-reduced water (ERW) which is produced near cathode during electrolysis of water scavenges reactive oxygen species and protects DNA from oxidative damage (Shirahata et al., 1997). Most of cancer cells exhibit high telomerase activity to elongate telomere length, insuring their immortality…
Changes in the Relevant Test Parameters of 101 Diabetes Patients under the Influence of the So-Called “Nordenau-Phenomenon”
The study examined changes in the test parameters of 101 diabetes patients (56 female, 45 male) under the influence of what is known as the “Nordenau Phenomenon”, which attributes a healing effect to an old slate tunnel with an underground spring. The average age of the test persons was 67,9 years…
Reduced Water for Prevention of Diseases
Although water is a very stable substance, it is easily electrolyzed to produce hydrogen and oxygen molecules. Weak current produces only active hydrogen and hydrogen molecule without production of oxygen molecule. Active hydrogen is so small that almost all minerals adsorbs or absorbs it. These…
Systemic and local effects of long-term exposure to alkaline drinking water in rats
Alkaline conditions in the oral cavity may be caused by a variety of stimuli, including tobacco products, antacids, alkaline drinking water or bicarbonate toothpaste. The effects of alkaline pH on oral mucosa have not been systematically studied. To assess the systemic (organ) and local (oral…
Anti-Oxidative Water Improves Diabetes
Electrolyzed reduced water and natural waters such as Hita Tenryosui water in Japan, Nordenau water in Germany and Tracote water in Mexico, which are known to improve various diseases, were all and- oxidative waters which could scavenge intracellular reactive oxygen species. The and-oxidative…
Suppressive Effect of Electrolyzed-Reduced Water on the Growth of Cancer Cells and Microorganisms
We investigated the suppressive effect of electrolyzed reduced water (ERW) on the growth of not only various human cancer cells but also microorganisms such as gram-negative Escherichia coli. ERW suppressed the growth of cancer cells, especially in soft-agar culture. The suppressive effect of ERW…
Antioxidant effects of reduced water produced by electrolysis of sodium chloride solutions
Antioxidant vitamins and enzymes such as superoxide dismutase, catalase and glutathione peroxidase are considered to function as scavengers against reactive oxygen species and to provide protection against reactive oxygen species, including free radicals. Although antioxidants such as L-ascorbic…
Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation
Molecular hydrogen reacts with the hydroxyl radical, a highly cytotoxic species produced in inflamed tissues. It has been suggested therefore to use gaseous hydrogen in a new anti-inflammatory strategy. We tested this idea, with the aid of the equipment and skills of COMEX SA in Marseille, a group…
Influences of alkaline ionized water on milk electrolyte concentrations in maternal rats
We previously reported that body weight on day 14 after birth in male offspring of rats given alkaline ionized water (AKW) was significantly heavier than that in offspring of rats given tap water (TPW), but no significant difference was noted in milk yield and in suckled milk volume between the two…
Fundamental Properties of Electrolyzed Water
Electrolyzed Water (Acidic Electrolyzed Water, Alkaline Electrolyzed Water) has recently attracted the interest of researchers in various fields such as medicine, agriculture and food processing. in this study, we investigated the preservability of Electrolyzed Water produced in a two-cell…
On the Physiology of Hydrogen Diving and Its Implication for Hydrogen Biochemical Decompression
Biochemical decompression, a novel approach for decreasing decompression sickness (DCS) risk by increasing the tissue washout rate of the inert gas, was tested in pigs during simulated H2 dives. Since there is only limited physiological data on the use of H2 as a diving gas, direct calorimetry…
Effectiveness of Electrolyzed Oxidized Water Irrigation in a Burn-Wound Infection Model
The purpose of the study was to determine whether electrolyzed oxidized water (EOW) functions as a bactericide in burn injury with Pseudomonas aeruginosa infection in a rat burn-wound model. Anesthetized Sprague-Dawley rats (n = 31) were subjected to third-degree burns to 30% of total body surface…
Changes in maximal performance of inspiratory and skeletal muscles during and after the 7.1-MPa Hydra 10 record human dive
During the 7.1-MPa hydrogen-helium-oxygen record human dive, we tested the hypothesis that the increased ambient pressure would alter the maximal muscle performance, specifically that breathing dense gas would lead to fatigue of the respiratory muscle. A group of hand muscles (adductor pollicis…