Breath hydrogen produced by ingestion of commercial hydrogen water and milk
Akito Shimouchi, Hiroshi Ishiguro, Kazutoshi Nose, Makoto Yamaguchi, Takahara Kondo
Read more:
DOI:
10.4137/bmi.s2209
DOI is the universal ID for this study.
This link will take you to the full study.
Abstract:
Objective: To compare how and to what extent ingestion of hydrogen water and milk increase breath hydrogen in adults.
Methods: Five subjects without specific diseases, ingested distilled or hydrogen water and milk as a reference material that could increase breath hydrogen. Their end-alveolar breath hydrogen was measured.
Results: Ingestion of hydrogen water rapidly increased breath hydrogen to the maximal level of approximately 40 ppm 10-15 min after ingestion and thereafter rapidly decreased to the baseline level, whereas ingestion of the same amount of distilled water did not change breath hydrogen (p < 0.001). Ingestion of hydrogen water increased both hydrogen peaks and the area under the curve (AUC) of breath hydrogen in a dose-dependent manner. Ingestion of milk showed a delayed and sustained increase of breath hydrogen in subjects with milk intolerance for up to 540 min. Ingestion of hydrogen water produced breath hydrogen at AUC levels of 2 to 9 ppm hour, whereas milk increased breath hydrogen to AUC levels of 164 ppm hour for 540 min after drinking.
Conclusion: Hydrogen water caused a rapid increase in breath hydrogen in a dose-dependent manner; however, the rise in breath hydrogen was not sustained compared with milk.
| Publish Year |
2009 |
| Country |
Japan |
| Rank |
Neutral |
| Journal |
Biomarker Insights |
| Primary Topic |
Whole Body |
| Secondary Topic | Hydrogen Biology |
| Model |
Human |
| Tertiary Topic | Hydrogen Safety |
| Vehicle |
Gas |
| pH |
N/A |
| Application |
In Vivo Biotic Production |
| Comparison |
|
| Complement |
|
NIR-Activatable Heterostructured Nanoadjuvant Cop/Nicop Executing Lactate Metabolism Interventions ...
2023 - Whole Body - Immune Regulation
Near-infrared (NIR) laser-induced photoimmunotherapy has aroused great interest due to its intrinsic non-invasiveness and spatiotemporal precision, while immune evasion evoked by lactic acid (LA) accumulation severely limits its clinical outcomes. ...
Micromotor-Enabled Active Hydrogen and Tobramycin Delivery for Synergistic Sepsis Therapy
2023 - Whole Body - Sepsis
Sepsis is a highly heterogeneous syndrome normally characterized by bacterial infection and dysregulated systemic inflammatory response that leads to multiple organ failure and death. Single anti-inflammation or anti-infection treatment exhibits ...
Evaluation of the safety and potential lipid-lowering effects of oral hydrogen-rich coral calcium ...
2023 - Whole Body - Metabolic Syndrome
Background: Metabolic syndrome is characterized by a cluster-like occurrence of conditions such as hypertension, hyperglycaemia, elevated low-density lipoprotein (LDL) cholesterol or triglycerides (TG) and high visceral fat. Metabolic syndrome is ...
Diffusivity of various inert gases in rat skeletal muscle
1975 - Whole Body - Hydrogen Biology
Krogh's diffusion constant (K) was determined for various inert gases in isolated rat abdominal muscle at 37 degrees C by measuring the amount of gas diffusing per unit time and partial pressure difference through a portion of the muscle of known ...
Solubility of various inert gases in rat skeletal muscle
1975 - Whole Body - Hydrogen Biology
For the determination of solubility coefficients, isolated rat abdominal muscles were equilibrated at 37 degrees C with various inert gases saturated with water vapor. After rapid transfer into a closed chamber containing room air the amount of gas ...
Solubility of inert gases in dog blood and skeletal muscle
1980 - Whole Body - Hydrogen Biology
Solubility of H2, Ar, CH4 and SF6 was determined at 310 K (37 degrees C) in water, in saline (0.154 mol NaCl/l H2O), in plasma and whole blood of dogs, and in homogenates of the dog gastrocnemius muscle. The liquids were equilibrated with pure gases, ...