Molecular hydrogen enhances osteogenesis in Danio rerio embryos

Giuseppe Banfi, Marta Carnovali, Massimo Mariotti

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DOI: 10.1111/jfb.14670 DOI is the universal ID for this study.

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Molecular hydrogen (H2 ) has been reported to have important biological effects on bone tissue in several in vitro and in vivo models. Danio rerio (zebrafish) embryo is a good model to study osteogenesis because its transparency, size and rapid development. In zebrafish embryo, hydrogen rich water (HRW) do not affect vitality or growth rate up to 15%. In addition, 7% HRW treatment enhances zebrafish embryo osteogenesis increasing vertebral mineralization rate. In conclusion, we demonstrated the beneficial effects of hydrogen on anabolic bone functions in vivo. This article is protected by copyright. All rights reserved.

Publish Year 2021
Country Italy
Rank Positive
Journal Journal of Fish Biology
Primary Topic Bone
Secondary TopicOsteogenesis
Model Zebrafish
Tertiary TopicMineralization Rate
Vehicle Water (Electrolysis)
pH Neutral
Application Immersion