Influences of alkaline ionized water on milk electrolyte concentrations in maternal rats

Eiji Murasugi, Hiroshi Kamata, In-Jen Pan, Kazuhiro Uwatoko, Toshi Watanabe, Tsuneo Sato, Youichi Fukuda

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DOI: 10.2131/jts.25.5_417 DOI is the universal ID for this study.

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We previously reported that body weight on day 14 after birth in male offspring of rats given alkaline ionized water (AKW) was significantly heavier than that in offspring of rats given tap water (TPW), but no significant difference was noted in milk yield and in suckled milk volume between the two groups. Additionally, the offspring in the AKW group and TPW group were given AKW and TPW, respectively, at weaning, and unexpectedly, the necrotic foci in the cardiac muscle were observed at the 15-week-old age in the AKW group, but not in the TPW group. The present study was designed to clarify the factors which are involved in that unusual increase of body weight and occurrence of cardiac necrosis. Eight dams in each group were given AKW or TPW (control) from day 0 of gestation to day 14 of lactation. The milk samples were collected on day 14 of lactation and analyzed for concentrations of calcium (Ca), sodium (Na), potassium (K), magnesium (Mg) and chloride (Cl). The AKW and TPW were also analyzed. Ca, Na and K levels in milk were significantly higher in the AKW group compared to the TPW group. No significant difference was noted in the Mg and Cl levels between the two groups. These data suggested that the Ca cation of AKW enriched the Ca concentration of the milk and accelerated the postnatal growth of the offspring of rats given AKW.

Publish Year 2001
Country Japan
Rank Positive
Journal Journal of Toxicological Sciences
Primary Topic Pregnancy
Secondary TopicMilk Production
Model Rat
Tertiary TopicElectrolytes
Vehicle Water (Electrolysis)
pH Alkaline
Application Ingestion