In vitro bactericidal activity against periodontopathic bacteria by electrolyzed ion-reduced water
F. hino, Fumiyoshi Ishii, K. Shimokawa, M. Kanzaki, Masahiro Okajima, Y. Ishibashi, Y. Kitahara, Y. Wada
Abstract:
As typical periodontopathic bacteria, Porphyromonas gingivalis (P. gingivalis) and Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) were exposed to electrolyzed ion-reduced water (ERI) and ERI containing 1% sodium carboxymethylcellulose (CMC-Na) (ERI-1% CMC-Na), and the time course of their bactericidal action was evaluated. More than 99% of each bacteria species were killed after exposure to each solution for 15 sec. In addition, 1% CMC-Na, which was added to prolong bactericidal action, did not affect the bactericidal action of ERI. Its bactericidal action was concentration-dependent. No viable P. gingivalis bacteria were observed at a concentration of 15% of the undiluted solution and no viable A. actinomycetemcomitans bacteria were observed at a concentration of 50%, indicating differences in the bactericidal action of ERI for the two bacteria species. These results suggest that ERI may be extremely useful in preventing and treating periodontal diseases.
| Publish Year |
2011 |
| Country |
Japan |
| Rank |
Positive |
| Journal |
Drug Discoveries and Therapeutics |
| Primary Topic |
Mouth |
| Secondary Topic | Periodontitis |
| Model |
Cell Culture |
| Tertiary Topic | Bacterial Infection |
| Vehicle |
Water (Electrolysis) |
| pH |
Alkaline |
| Application |
Culture Media |
| Comparison |
|
| Complement |
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