Clinical study of hydrogen-rich saline in the treatment of moderate to severe allergic rhinitis

J. Jin, M.L. Qin, Q. Ge, S.Q. Yu, X. Zhang, X.L. Zhang, Y. Wang

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DOI: 10.13201/j.issn.1001-1781.2018.07.004 DOI is the universal ID for this study.

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Objective:To investigate the effectiveness and safety of nasal lavage with hydrogen-rich saline in the treatment of moderate to severe allergic rhinitis.Method:Twenty patients with moderate to severe persistent allergic rhinitis were treated with normal saline and hydrogen-rich saline lavage the nasal cavity. The study was randomized doubl-blind self-control study. The symptoms and signs score, treatment index and total effective rate were evaluated before and after treatment, and the nasal conjunctivitis related quality of life questionnaire (BQLQ) was used to evaluate the life quality of patients.Result:There were significant differences of the symptoms, signs scores, the treatment index, the total efficiency and BQLQ between the two kinds of lavage fluid used for patients before and after treatment(P<0.05). No significant adverse reactions occurred during follow-up.

Conclusion:Hydrogen-enriched saline is safe and effective for allergic rhinitis.

Publish Year 2018
Country China
Rank Positive
Journal Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Primary Topic Nose
Secondary TopicRhinitis
Model Human
Tertiary TopicInflammation
Vehicle Saline (Dissolved)
pH Neutral
Application Irrigation