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Studies Found: 1335

BONE MARROW - CANCER

Protective effects of hydrogen gas inhalation on radiation-induced bone marrow damage in cancer ...

Year Published: 2021

Although intensity-modulated radiation therapy (IMRT) has been developed as an alternative to conventional radiotherapy, reducing bone marrow damage is limited. Thus, a novel technology is needed to further mitigate IMRT-induced bone marrow damage. Molecular hydrogen (H2) was recently reported as a preventive and therapeutic antioxidant that selectively scavenges hydroxyl radical (·OH) and ...
WHOLE BODY - STRESS RESILIENCE

Alleviation of the chronic stress response attributed to the antioxidant and anti-inflammatory ...

Year Published: 2021

Reactive oxygen species (ROS) are highly reactive and directly attack surrounding biomolecules to deteriorate cellular and tissue functions. Meanwhile, ROS also serve as signaling mediators to upregulate pro-inflammatory cytokine expression via activation of the nuclear factor kappa B signaling pathway, and the increased pro-inflammatory cytokines trigger respiratory burst of inflammatory cells ...
PENIS - SURGERY/TRANSPLANTATION

Protective effects of hydrogen rich saline solution on ventral penile mathieu type flap with penile ...

Year Published: 2021

Introduction: Penile tourniquet (Pt) application aims to work in a bloodless field in penile surgery. When the tourniquet is released, reperfusion injury occurs with the resumption of blood flow. Molecular hydrogen can easily attach to biomembranes and enter cytosol, mitochondria and other organelles of the cell and convert the formed OH- to H₂O to prevent cell and tissue damage. Aim: We ...
SKIN - COSMETIC ISSUES

Effects of Topical Hydrogen Purification on Skin Parameters and Acne Vulgaris in Adult Women

Year Published: 2021

Background: Acne vulgaris is a prevalent dermatological disease characterized by skin eruptions, which may decrease the sufferer's quality of life. Hydrogen purification treatment is a new procedure used in cosmetology to improve the skin parameters of the face. This study examined the effectiveness of hydrogen purification treatment to improve women's skin conditions with regard to acne vulgaris. ...
HEART - EXCERCISE

Acute hydrogen-rich water ingestion stimulates cardiac autonomic activity in healthy females

Year Published: 2021

Background: Hydrogen-rich water (HRW) has been shown to have a stimulating effect on the human body. Objective: The aim of the study was to assess the influence of acute HRW intake on autonomic cardiac regulation during 50 min of rest sitting. Methods: Fourteen healthy females (age 21.7 ± 1.2 years, body mass 67.8 ± 8.7 kg, height 167 ± 5.5 cm) took part in this double-blind, randomized, ...
WHOLE BODY - AGING

High-flow hydrogen inhalation might suppresses the immune function of middle-aged participants: a ...

Year Published: 2021

Hydrogen inhalation therapy has been proven to be safe and effective in disease treatment in multiple clinical reports, but the gas flow rates used in different studies vary greatly. Since there is no upper limit for the safe concentration of hydrogen, this study tested the effects of high-flow (not high concentration) hydrogen inhalation on immune function. From October 2019 to January 2020, 20 ...
BONE - OSTEOGENESIS

Molecular hydrogen enhances osteogenesis in Danio rerio embryos

Year Published: 2021

Molecular hydrogen (H2 ) has been reported to have important biological effects on bone tissue in several in vitro and in vivo models. Danio rerio (zebrafish) embryo is a good model to study osteogenesis because its transparency, size and rapid development. In zebrafish embryo, hydrogen rich water (HRW) do not affect vitality or growth rate up to 15%. In addition, 7% HRW treatment enhances ...
BRAIN - SEPSIS

Hydrogen alleviated neuronal injury and neuroinflammation induced by microglial activation via the ...

Year Published: 2021

Objective: Sepsis-associated encephalopathy (SAE) is characterized by diffuse cerebral and central nervous system (CNS) dysfunction. Microglia play a vital role in protecting the brain from neuronal damage, which is closely related to inflammatory responses. The Nrf2 signaling pathway has an impact on microglial and neuronal injury. Here, we mainly explored the molecular mechanism by which H2 ...
WHOLE BODY - EXCERCISE

Hydrogen Rich Water Consumption Positively Affects Muscle Performance, Lactate Response, and ...

Year Published: 2021

Hydrogen rich water consumption positively affects muscle performance, lactate response, and alleviates delayed onset of muscle soreness after resistance training. J Strength Cond Res XX(X): 000-000, 2021-Positive outcomes of hydrogen rich water (HRW) supplementation on endurance performance have been shown, but the effects of HRW in resistance training are unclear. The aim of this study was to ...
WHOLE BODY - EXCERCISE

Fukuoka, Yoshiyuki

Year Published: 2021

We investigated effects of molecular hydrogen (H2) supplementation on acid-base status, pulmonary gas exchange responses, and local muscle oxygenation during incremental exercise. Eighteen healthy, trained subjects in a randomized, double-blind, crossover design received H2-rich calcium powder (HCP) (1500 mg/day, containing 2.544 µg/day of H2) or H2-depleted placebo (1500 mg/day) for three ...